Arylation and Heteroarylation of Thienylsulfonamides with Organotrifluoroborates

نویسندگان

  • Mnaza Noreen
  • Nasir Rasool
  • Mirna El Khatib
  • Gary A. Molander
چکیده

A mild, practical protocol has been developed for the Suzuki cross-coupling of unprotected thienylsulfonamides from air- and bench-stable organotrifluoroborates in the absence of a protecting group on the sulfonamide nitrogen. The developed synthetic method can be applied to the preparation of various arylated and heteroarylated thienylsulfonamides under conditions that are tolerant of a broad range of functional groups.

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عنوان ژورنال:

دوره 79  شماره 

صفحات  -

تاریخ انتشار 2014